Selank extends the tuftsin sequence (TKPR) with a Pro-Gly-Pro tail that markedly increases stability. Published work reports anxiolytic effects described as comparable to classical benzodiazepines but without the sedation and dependence profile; the proposed mechanism involves modulation of the interaction…
Semax is ACTH(4-10) with a C-terminal Pro-Gly-Pro extension that confers stability while stripping the hormonal activity of the parent fragment. A single application in rats has been reported to raise hippocampal BDNF protein about 1.4-fold with a roughly 3-fold increase…
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