Specification
Purity>99% (HPLC + MS)
FormLyophilised powder
Box10 sealed vials
SourceSweden
Storage-20 °C, dark, sealed
Reconstituted2–8 °C
Certificate of analysis
Every box carries a batch number. Look it up and you get the analytical data for the exact vials you received.
Batch lookup →SS-31
Elamipretide, MTP-131, Bendavia
A cell-permeable tetrapeptide that concentrates in the inner mitochondrial membrane by binding cardiolipin — the leading mitochondria-targeted research peptide.
Research use only. This compound is supplied for laboratory research. It is not a medicine or supplement, is not approved for human use, and no dosing guidance for humans is offered here or by our team. Handle under appropriate laboratory conditions. Full disclaimer →
What the literature describes
SS-31 belongs to a class of amphipathic tetrapeptides with an alternating aromatic–cationic motif that allows them to cross membranes and accumulate in the inner mitochondrial membrane, where they associate with the anionic phospholipid cardiolipin. Published mechanisms include re-energising ischaemic mitochondria via cardiolipin interaction, modulation of membrane surface electrostatics, and improved ADP sensitivity in aged mitochondria through the adenine nucleotide translocator. Independent groups have reported efficacy in models of cardiomyopathy, skeletal muscle atrophy, ischaemia-reperfusion injury and neurodegeneration.
Available sizes & pricing
Prices in USD per sealed box of 10 vials. Bulk pricing available from 10 boxes — see wholesale.
| Vial strength | Box | Price | |
|---|---|---|---|
| 5mg | 10 vials |
$106.40
$10.64 per vial
|
Order 5mg |
| 10mg | 10 vials |
$173.60
$17.36 per vial
|
Order 10mg |
| 50mg | 10 vials |
$672
$67.20 per vial
|
Order 50mg |
Published research
Links open peer-reviewed sources on PubMed. These are provided so you can read the primary literature yourself. Citing a study is not a claim that this compound is safe or effective for any use in humans.
- The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipinPubMed
- The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria via the adenine nucleotide translocatorPubMed
- Elamipretide improves cardiac and skeletal muscle function during agingPubMed
- SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanismPubMed Central — free full text
- All indexed literature on elamipretide (PubMed search)PubMed search
Research areas
Studied in the same area
